Advanced RGN-6 is a regenerative cream designed to visibly reverse 6 signs of aging and skin tone damage. Inspired by laser regeneration science, this patented formula is powered by 6 core ingredients to help reverse signs of aging, like redness, stubborn discoloration, and wrinkles for a rejuvenated appearance with visible results starting in just 1 week. It is free of fragrance, parabens, and alcohol - making it ideal for sensitive skin.

Built on over 5 years of extensive research and innovation, inspired by laser regeneration science. Laser treatments can combat aging and uneven skin tone by creating controlled micro-damage that stimulates collagen production and skin regeneration, resulting in a smoother, tighter, and brighter complexion.

Advanced RGN-6 is developed to be used both as part of a daily skincare routine, and alongside in-office laser procedures. Physician tested to complement laser procedures for optimal anti-aging results, Advanced RGN-6 helps reduce downtime post-procedure, aiding the skin in appearing less rough, smoother, more hydrated. It is physician tested with laser on all skin tones. Ad Advanced RGN-6's exclusive, multi-patented ingredient technology promotes barrier repair, improves appearance of discoloration, and reduces visible redness post-treatment.

POWERFUL WHEN USED ALONE

In a 12-week clinical study, Advanced RGN-6 significantly improved the appearance of key indicators of daily skin damage:

• 69% Reduction in visible redness

• 36% Reduction in post-acne marks

• 26% Reduction in dark spots

• 18% Reduction in wrinkles

• 35% Increase in smoothness

• 35% Increase in firmness

SkinCeuticals Hydrating B5 Serum

A hydrating, hyaluronic acid serum that replenishes moisture and restores radiance for a smoother complexion. The oil-free formula also contains vitamin B5 for acne-prone skin.

RECOMMENDED FOR

• Dry

• Normal

• Combination

• Sensitive

• Sensitized

• Dehydrated

• Blemish-prone

• Ageing

Hydrating B5 Serum Benefits

• Leaves skin feeling supple and smooth

• Enhances the benefits of a daily moisturiser

• Provides optimal hydration without clogging pores

• Paraben-, alcohol-, dye-, fragrance-free

• Ideal for all skin types

Hydrating B5 Serum

Enriched with vitamin B5 to enliven the skin, SkinCeuticals Hydrating B5 Serum replenishes the nutrients required for skin to feel smooth and appear younger. An oil-free, hydrating serum that replenishes moisture and restores radiance for a smoother complexion, this revitalising serum also harnesses the power of hyaluronic acid – the body’s natural hydrator – to assist in binding moisture to the skin. This results in a hyaluronic acid serum that, along with vitamin B5, provides powerful antioxidant protection.

SkinCeuticals Hydrating B5 complements Triple Lipid Repair 2:4:2 Anti-Ageing Moisturiser and is particularly beneficial for hydrating oily, acne-prone skin.

The Science Behind Hydrating B5 Serum

What is Skin Dehydration?

Skin dehydration occurs when the skin is severely lacking water. This can appear as dryness, uneven skin tone, a change in complexion, and fine lines on the skin. Hyaluronic acid is a naturally occurring humectant, drawing in and retaining moisture to keep skin hydrated. Retaining up to 1,000 times its weight in water, hyaluronic acid helps prevent trans-epidermal water loss. Vitamin B5 is another moisturising skin ingredient.

Skin Hydration DOs + DON’Ts

DO: Apply After Microneedling

Help skin’s rejuvenation after a microneedling treatment by following with hyaluronic acid. Together, the two keep skin looking plump and healthy by aiding skin cell turnover and improving the complexion.

DON’T: Apply Improperly

To maximise the effects of Hydrating B5, always apply your products from thinnest to thickest texture.

Hydrating B5 + Hydrafacials

Address skin dehydration by combining Hydrating B5 with a powerful aesthetic Pro treatment. A HydraFacial uses patented technology to cleanse, extract, and hydrate skin while infusing highly effective serums tailored to your specific skin needs. This unique process helps improve the appearance of several skin concerns, including fine lines, wrinkles, skin firmness, texture, and pore congestion.

Phloretin CF Vitamin C Serum

Vitamin C serum for discolouration

RECOMMENDED FOR

• Normal

• Oily

• Combination

• Discolouration

• Blemishes

• Ageing

Phloretin CF Benefits

• Provides advanced environmental protection by neutralising damaging free radicals

• Improves the appearance of discolouration to improve overall skin tone

• Once absorbed, this vitamin C serum remains effective for a minimum of 72 hours

• Paraben-, fragrance-, and dye-free

• Ideal for normal skin, oily skin, and combination skin types

Product Benefits

SkinCeuticals Phloretin CF Serum contains an array of skincare ingredients that work in combination to deliver exceptional results. The formula includes 2% phloretin, 10% pure vitamin C (L-ascorbic acid), and 0.5% ferulic acid, proven to target atmospheric ageing, visibly reduce environmental damage to skin, and diminish premature signs of ageing. Antioxidants help neutralise free radicals and address damage caused by exposure to UV rays, infrared radiation (IRA), and ozone pollution (O3).

In addition to its protective antioxidant benefits, Phloretin CF improves the appearance of discolouration, fine lines, and uneven skin tone. Clinical studies show results including a more even skin tone, increased radiance, and overall reduction in discolouration.

In vivo, Phloretin CF provides a high level of environmental protection against UV-induced oxidative damage under simulated sunlight. After 24 weeks of use, it has been shown to reduce fine lines by 24%, improve skin texture by 16%, and reduce dullness and discolouration by 19%.

Phloretin CF is also proven to be safe post-CO₂ cryotherapy treatment, delivering a statistically significant improvement in skin smoothness and general appearance within one week compared to untreated lesions.

For optimal daily protection, pair Phloretin CF with a broad spectrum sunscreen. When used together, SkinCeuticals antioxidants and sunscreens provide comprehensive defence against visible ageing caused by environmental aggressors.

SkinCeuticals Antioxidant AOX Vitamin C Eye Gel 15ml

An eye serum in a lightweight gel that provides advanced environmental protection around the eyes while reducing the look of puffiness, visible signs of fatigue, and under eye circles.

AOX+ Eye Gel is a unique serum-in-a-gel that contains a synergistic combination of 5% pure vitamin C (l-ascorbic acid), 1% phloretin, and 0.5% ferulic acid along with powerful botanicals to protect the delicate eye area from environmental skin ageing – environmental damage and premature signs of ageing caused by free radicals from UV rays, infrared radiation (IRA), and ozone pollution (O3). This refreshing eye serum targets visible signs of ageing such as crow’s feet and fine lines and improves the appearance of puffiness, fatigue, and under eye circles.

Environmental Aggressors + Eyes

Environmental aggressors, such as pollution or sunlight, cause free radical damage that leads to premature, visible signs of ageing. The delicate, thin skin around the eye is especially prone to damage from environmental aggressors. To prevent discolouration, fine lines, and wrinkles, incorporate an antioxidant-rich serum that offers environmental protection.

C E Ferulic® Benefits

C E Ferulic offers a range of powerful benefits for the skin. It provides advanced protection against environmental aggressors by neutralising damaging free radicals. This results in visible anti-ageing effects, including a reduction in the appearance of lines and wrinkles, improved firmness, and a brighter, more radiant complexion. Once absorbed, the serum remains effective for at least 72 hours. It’s ideal for normal and dry skin types and is completely paraben-free.

C E Ferulic Vitamin C Serum

SkinCeuticals C E Ferulic is a high-potency antioxidant serum formulated to protect against atmospheric ageing. It combines 15% pure vitamin C (L-ascorbic acid), 1% vitamin E (alpha tocopherol), and 0.5% ferulic acid to defend against environmental damage and the premature signs of ageing caused by free radicals from UV rays, infrared radiation (IRA), and ozone pollution (O₃).

Science and Proof

SkinCeuticals research demonstrates that specific combinations of antioxidants, when carefully formulated, work synergistically to produce better results than individual ingredients alone. Vitamin C is a potent antioxidant, but its instability makes it difficult to deliver effectively to the skin. The patented formulation of C E Ferulic—developed under the Duke Antioxidant patent—has solved this challenge and has been published in eight peer-reviewed scientific journals.

This formulation is based on three essential parameters for delivering vitamin C effectively:

• Use pure vitamin C (L-ascorbic acid)

• At a concentration of 10%–20%

• Maintain an acidic pH between 2.0–3.5

Clinically Proven Results

Clinical studies have shown that C E Ferulic delivers visible and measurable improvements in skin:

• 37% increase in firmness

• 27% reduction in the appearance of fine lines

• 36% reduction in the appearance of wrinkles

Protecting Skin from Environmental Aggressors

Environmental aggressors such as sunlight, air pollution, and metals produce free radicals that cause oxidative stress and speed up visible ageing. Daily use of an antioxidant like vitamin C can help neutralise these free radicals and protect the skin from long-term damage. C E Ferulic is specially designed for this purpose, with a formulation that directly targets and reduces oxidative stress.

Our Formulation Superiority

Developed by Dr. Pinnell at Duke University, the Duke Antioxidant patent defines the precise conditions for optimal delivery of vitamin C to the skin. It outlines the combination of L-ascorbic acid, a 10–20% concentration, and an acidic pH (2.0–3.5) as key to formulation success. This scientific innovation also enabled vitamin C, a water-soluble antioxidant, to be combined with vitamin E, a lipid-based antioxidant, for superior skin protection.

Gold Is the Standard

It’s completely normal for C E Ferulic to appear gold or amber in colour either upon opening or over time. This is due to the presence of pure vitamin C and does not indicate reduced effectiveness. Regardless of colour changes, testing confirms that the active ingredients remain potent for up to 36 months.

Use With Non-Ablative Laser Treatments

C E Ferulic pairs effectively with non-ablative laser treatments, which work by triggering the skin’s natural wound-healing response to increase collagen production and cellular renewal. Using this serum before or after laser procedures can boost results and help shorten recovery time by visibly reducing redness and swelling.

Resveratrol B E® Antioxidant Night Serum

Concentrated overnight antioxidant repair for visibly firmer, more radiant skin.

Product Overview

Resveratrol B E is a powerful nighttime antioxidant serum designed to support the skin’s natural repair processes while you sleep. This concentrated treatment contains a synergistic blend of 1.0% resveratrol, 0.5% baicalin, and 1.0% pure vitamin E (alpha tocopherol) to help combat visible signs of ageing and oxidative damage. Over time, it works to improve skin radiance, firmness, density, and overall texture.

Recommended For

• Dry skin

• Normal skin

• Combination skin

• Sensitive skin

• Ageing skin

Key Benefits

• Neutralises free radicals caused by environmental stressors and supports the skin’s own antioxidant defences

• Diminishes visible signs of ageing including loss of firmness, dullness, and fine lines

• Improves the appearance of skin radiance, firmness, elasticity, and density

• Paraben-free, fragrance-free, and dye-free

• Ideal for nighttime use on normal, dry, and combination skin types

Science + Proof

Clinically Proven Results

In a 12-week, dermatologist-controlled clinical trial, Resveratrol B E demonstrated significant improvements in skin texture, elasticity, and density:

• 18% improvement in skin density

• 20% increase in epidermal thickness

• 19% improvement in smoothness

• 13% improvement in elasticity

• 10% improvement in radiance and firmness

Additional biological markers of skin health also improved:

• 3-fold reduction in VEGF (a marker of inflammation and oxidative stress)

• 1.5-fold increase in Collagen I and Collagen III, which support structural skin repair and firmness

Study Protocol

This study included 55 women aged 45–60 with mild-to-moderate lines, discolouration, and laxity. Participants used Resveratrol B E once nightly, alongside SkinCeuticals Gentle Cleanser and Emollience Moisturiser as needed. (USA, 2013)

The Science Behind Resveratrol B E

Nighttime Repair Technology

Skin is most receptive to repair overnight, when cellular activity peaks and environmental exposure is reduced. Resveratrol B E leverages this window by delivering a potent blend of antioxidants to support the skin’s natural renewal process and reduce oxidative stress.

The Power of Resveratrol

Often called the “longevity molecule,” resveratrol is a powerful antioxidant derived from red grapes and other botanicals. In skincare, it helps neutralise free radicals, support collagen production, and reduce inflammation, making it a key ingredient in anti-ageing formulas. When combined with baicalin and vitamin E, its effects are amplified—restoring a firmer, more youthful appearance overnight.

Silymarin CF® Vitamin C Serum

Advanced antioxidant protection for oily and blemish-prone skin.

Product Overview

Silymarin CF is a breakthrough oil-free vitamin C serum specifically formulated for oily and blemish-prone skin. This potent formula combines 0.5% silymarin (milk thistle extract), 15% pure L-ascorbic acid, 0.5% ferulic acid, and 0.5% salicylic acid to target oil oxidation, refine texture, and visibly improve clarity and fine lines.

By preventing the oxidation of sebum—one of the main causes of blemishes—Silymarin CF offers powerful protection against environmental aggressors while promoting clearer, smoother, more radiant skin.

Recommended For

• Normal skin

• Oily skin

• Combination skin

• Skin discolouration

• Blemish-prone skin

• Ageing concerns

Key Benefits

• Provides advanced antioxidant protection from environmental aggressors

• Helps prevent oil oxidation that can trigger breakouts

• Minimises the appearance of pores and refines skin texture

• Improves skin clarity, radiance, and uneven tone

• Reduces the appearance of fine lines and wrinkles

• Visibly reduces excess oil and shine

Science + Proof

Clinically Proven Results

Silymarin CF has been shown to significantly improve key markers of oily and blemish-prone skin:

• 27% reduction in blemishes

• 38% improvement in skin texture

• 25% improvement in skin clarity

These results demonstrate the serum’s dual action: offering antioxidant protection while visibly improving skin’s appearance and balance.

The Science Behind Silymarin CF

Targeted Antioxidant Protection

While all vitamin C serums offer protection from free radicals, Silymarin CF is specifically designed to combat oil oxidation—a newly recognised contributor to blemish formation. When excess oil oxidises, it creates damaging free radicals that can irritate pores and accelerate signs of ageing. This formula addresses that process at the source.

Regulate Oil and Prevent Breakouts

Silymarin, an antioxidant extracted from milk thistle, helps reduce the oxidative stress caused by sebum buildup. Paired with salicylic acid, this serum helps to regulate oil production, improve skin clarity, and reduce the likelihood of blemishes and visible pores—without drying or stripping the skin.

Ideal Pairing With Aesthetic Treatments

Silymarin CF complements a wide range of professional retexturing treatments such as chemical peels, microneedling, and light therapies. These procedures help reduce sebum production and increase skin turnover—while Silymarin CF enhances results by protecting the skin from oxidative damage and boosting post-treatment clarity.

P-TIOX® Peptide Serum

Advanced wrinkle-reducing peptide serum for smoother, radiant, visibly younger-looking skin.

Product Overview

P-TIOX is a next-generation anti-wrinkle peptide serum clinically proven to reduce the appearance of nine types of expression lines by up to 20%. Formulated with an advanced multi-peptide complex, this targeted serum works to modulate muscle contraction lines and smooth visible wrinkles on the forehead, around the eyes, and between the eyebrows.

Enriched with 5% PHA, 5% niacinamide, and laminaria extract, the formula enhances skin texture, boosts radiance within 1 week, and supports long-term collagen and elastin production. With continued use, P-TIOX delivers visible, lasting anti-ageing results—leaving the skin plump, smooth, and revitalised.

Recommended For

• Dry skin

• Normal skin

• Oily skin

• Combination skin

• Sensitive skin

• Ageing concerns

• Fine lines and wrinkles

Key Benefits

• Visibly reduces 9 types of expression wrinkles by up to 20%

• Boosts radiance in just 1 week

• Improves skin texture, smoothness, and firmness over time

• Scientifically tested and proven effective across all skin tones

• Paraben-free, fragrance-free, and silicone-free

• Suitable for sensitive skin

The Science Behind P-TIOX

Formation of Expression Wrinkles

Expression wrinkles—also called mimetic wrinkles—form as a result of repeated muscle contractions on the face. Over time, these lines become more visible due to the natural loss of skin flexibility and lower concentrations of collagen, elastin, and hyaluronic acid. P-TIOX helps reduce and prevent these wrinkles by modulating their source: muscle contraction.

Multi-Peptide Complex for Proven Results

P-TIOX is formulated with a Multi-Peptide Complex, combining both hexapeptides and dipeptides, known to relax facial tension and reduce contraction lines. This formula is amplified with:

• 5% PHA to gently resurface and improve skin clarity

• 5% Niacinamide to even tone and strengthen the skin barrier

• Laminaria Extract to soothe and support antioxidant activity

Together, these actives work synergistically to create a superior wrinkle-smoothing serum with results that last beyond 3 months of use.

Collagen III Amplifier® Multi-Peptide Collagen Serum

Advanced collagen booster for visibly firmer, smoother, and deeply hydrated skin.

Product Overview

Collagen III Amplifier is a breakthrough collagen-stimulating peptide serum that targets key signs of collagen loss—texture, elasticity, fine lines, and firmness. Formulated with cutting-edge Biotech Collagen Type III and a potent multi-peptide complex, this serum visibly restores skin structure and promotes collagen regeneration from the surface up.

The formula delivers accelerated results in just one week*, along with up to 48 hours of deep hydration and a +28% improvement in the skin’s moisture barrier after just one hour of use**. Skin feels plumper, looks more radiant, and is visibly stronger, smoother, and more youthful.

Recommended For

• Normal skin

• Dry or dehydrated skin

• Ageing concerns

• Sensitised skin

• Dull or uneven skin tone

• Combination skin

Key Benefits

• Accelerates collagen production for firmer, more elastic skin in just 1 week*

• Strengthens skin’s moisture barrier by up to 28% in just 1 hour

• Provides 48-hour hydration to deeply nourish and smooth dry, dehydrated skin

• Helps improve the appearance of fine lines, wrinkles, firmness, and dullness

• Supports collagen Types I, III, and IV for multi-level repair and structural support

• Ideal for use between your vitamin C or resveratrol serum and moisturiser

Science + Proof

Clinically Proven Results

• +28% improvement in moisture barrier after 1 hour of use

• 48H hydration for long-lasting skin nourishment

• Visible results in 1 week: improved firmness, texture, and radiance

*Cosmeto-clinical study on 60 Chinese subjects using the serum twice daily

**Instrumental test on 25 subjects, 1 hour after application

The Science Behind Collagen III Amplifier

Biotech Collagen Type III: The Collagen of Repair

This advanced ingredient stimulates multiple types of collagen production in the skin, most notably Type III collagen, known for its regenerative and restorative properties. Collagen Type III helps rebuild elasticity, improve firmness, and restore skin density.

Multi-Level Collagen Support

In addition to Type III collagen, this serum helps promote Types I and IV, addressing multiple layers of the skin to visibly correct signs of collagen loss. Combined with hydrating peptides, glycerin, and barrier-supporting ingredients, the formula enhances both the structure and surface appearance of the skin.

Discoloration Defense® Dark Spot Corrector

Targeted daily serum for visible reduction in hyperpigmentation, post-acne marks, and uneven skin tone.

Product Overview

Discoloration Defense is a powerful, layerable daily-use serum formulated to correct visible skin discoloration and even out skin tone. Clinically proven to deliver brighter, clearer skin in as little as two weeks, this advanced corrector targets key types of pigmentation, including stubborn dark spots, post-acne marks, and blotchy tone.

Formulated with a synergistic blend of 3% tranexamic acid, 1% kojic acid, 5% niacinamide, and 5% HEPES, this serum is suitable for all skin tones and works without harsh ingredients like hydroquinone. It’s ideal as part of a long-term pigmentation protocol or as an at-home maintenance product alongside professional treatments.

Recommended For

• Dry skin

• Normal skin

• Oily or combination skin

• Sensitive skin

• Discoloration and uneven tone

• Hyperpigmentation and post-inflammatory marks

Key Benefits

• Visibly reduces hyperpigmentation by up to 59%*

• Improves the appearance of skin tone evenness by up to 59%*

• Features a non-irritating blend of anti-discoloration ingredients

• Hydroquinone-free, paraben-free, fragrance-free, and silicone-free

• Effective across all skin tones, including deeper complexions

• Pairs well with professional treatments like chemical peels and non-ablative laser

*Based on a 12-week cosmeto-clinical study with 55 subjects using the product twice daily with SPF 50+

Science + Proof

Clinically Proven Results

In a 12-week clinical study, participants experienced:

• 59% visible reduction in hyperpigmentation

• 59% improvement in the appearance of skin tone evenness

These results were achieved without the use of hydroquinone, making this serum a safe and effective choice for long-term discoloration management.

The Science Behind Discoloration Defense

What Causes Skin Discoloration?

Discoloration occurs when melanin production increases due to inflammation, sun exposure, or hormonal changes. This results in visible dark spots, post-acne marks, and uneven skin tone. Discoloration Defense targets these concerns at the source, helping to regulate pigmentation and restore clarity.

Discoloration Do’s + Don’ts

• ✅ DO: Use a broad-spectrum SPF 50+ sunscreen daily to prevent future pigmentation and protect your results

• ❌ DON’T: Skip antioxidants—incorporating a brightening serum like Discoloration Defense supports ongoing correction and radiance

• ✅ COMBINE: Discoloration Defense is an ideal complement to chemical peels and IPL (intense pulsed light) treatments, enhancing their results and preventing recurrence

Product Overview

A.G.E. Interrupter Ultra Serum is a next-generation anti-ageing treatment formulated to combat two major causes of visible skin ageing: collagen depletion and glycation. Powered by a clinically proven 34.6% concentration of Flavo-Proxylane, this advanced serum lifts and firms key facial zones—the jawline, cheeks, and forehead—for a visibly sculpted, youthful appearance.

Enhanced with Rhamnose and Gentiana Lutea Root Extract, this fast-absorbing serum strengthens the skin barrier, delivers 24-hour hydration, and visibly reduces the appearance of fine lines, wrinkles, and uneven texture. Dermatologically tested across all skin types and tones, including sensitive skin.

Recommended For

• Normal skin

• Oily skin

• Dry skin

• Combination skin

• Ageing skin (lines, laxity, dullness)

Key Benefits

• Improves elasticity in 3 key facial areas: jawline, cheeks, and forehead

• Lifts and redefines facial contours for a firmer, sculpted appearance

• Reduces forehead wrinkles by up to 14% and under-eye wrinkles by up to 17%

• Improves skin smoothness by 40% and radiance by 30%

• Provides +73% hydration in 1 hour and 24-hour moisturisation

• Strengthens the skin barrier and smooths visible signs of glycation

• Tested on all skin types and tones, including sensitive skin

Science + Proof

Clinically Proven Results

• +73% increase in skin hydration in 1 hour

• 40% improvement in overall skin smoothness

• 14% reduction in forehead lines

• 17% reduction in under-eye wrinkles

• 30% improvement in skin radiance

• Improved elasticity in 3 key facial areas (jawline, cheeks, forehead) within 12 weeks

• Tested on all skin tones and types.

The Science Behind A.G.E. Interrupter Ultra Serum

Understanding Glycation & Collagen Loss

Glycation is a natural ageing process in which excess sugars bind to collagen and elastin, forming damaging Advanced Glycation End-products (A.G.E.s). These molecules weaken the skin’s structure, leading to wrinkles, sagging, and dullness. A.G.E. Interrupter Ultra Serum is specifically formulated to counteract the effects of glycation and restore elasticity.

Formula Superiority

At the core of this formula is 34.6% Flavo-Proxylane, a skin-repairing molecule that targets glycation-related ageing and stimulates collagen renewal. Rhamnose and Gentiana Lutea Root Extract work alongside Flavo-Proxylane to lift and firm the skin, reduce visible wrinkles, and restore suppleness.

Ideal With Aesthetic Lifting Treatments

This serum pairs beautifully with clinic-based collagen stimulation procedures such as ultrasound skin tightening. While effective on its own, it’s also physician-tested to enhance and extend the results of lifting treatments.

A.G.E. Advanced Eye® for Dark Circles

Brightening, hydrating eye cream that targets crow’s feet, puffiness, and glycation-related ageing.

Product Overview

A.G.E. Advanced Eye is a next-generation brightening eye cream designed to combat visible signs of ageing in the delicate eye area. Formulated to reduce the impact of advanced glycation end-products (A.G.E.s)—a major contributor to eye-area ageing—this silky, fast-absorbing cream delivers hydration, brightening, and firming benefits.

With a potent blend of Proxylane™, Matrixyl 3000, flavonoids, glycyrrhetinic acid, caffeine, and optical diffusers, this targeted formula reduces the appearance of dark circles, crow’s feet, under-eye wrinkles, and puffiness. A cooling metal applicator tip provides instant depuffing while improving product absorption. Safe for all skin tones and types—including sensitive skin.

Recommended For

• Dry skin

• Normal skin

• Combination skin

• Ageing skin

• Eye concerns: dark circles, crow’s feet, puffiness, dehydration

Key Benefits

• Reduces crow’s feet by 18% and under-eye wrinkles by 23%

• Improves dark circles by 20% and puffiness by 24%

• Immediately brightens and enhances radiance for all skin tones

• Hydrates dry, ageing skin and strengthens the delicate eye area

• Features a cooling metal applicator to depuff and soothe

• Paraben-free, fragrance-free, and dye-free

• Dermatologist-tested and suitable for sensitive skin

Science + Proof

Clinically Proven Results

In clinical testing, A.G.E. Advanced Eye showed significant visible improvements in key signs of eye-area ageing:

• 23% improvement in under-eye wrinkles

• 24% reduction in puffiness

• 20% improvement in dark circles

• 18% reduction in crow’s feet

These results were observed with consistent twice-daily use and paired sun protection.

The Science Behind A.G.E. Advanced Eye

What Is Glycation Around the Eyes?

Glycation is a natural ageing process that occurs when sugar molecules bind to collagen and elastin, forming advanced glycation end-products (A.G.E.s). This process makes structural proteins brittle, accelerating the appearance of wrinkles, skin laxity, and loss of elasticity.

The eye area is particularly vulnerable due to its thin, delicate structure. A.G.E. Advanced Eye is formulated to counteract glycation-related signs of ageing while delivering hydration, firmness, and immediate brightening through inclusive optical diffusers.

Eye Area DOs and DON’Ts

• ✅ DO: Pair with broad-spectrum sunscreen and antioxidants to protect delicate skin from UV and environmental stress.

• ❌ DON’T: Expose your skin to smoke or pollutants, which accelerate glycation and worsen signs of ageing around the eyes.

A.G.E. Interrupter Advanced Anti-Wrinkle Cream

Target visible signs of skin ageing caused by glycation and collagen depletion.

Recommended For:

• Dry skin

• Normal skin

• Combination skin

• Sensitive skin

• Ageing concerns

Key Benefits

• Collagen-boosting formula with niacinamide and Proxylane™ helps improve skin firmness and reduce the look of deep wrinkles and fine lines.

• Targets glycation—a leading cause of collagen and elastin degradation—helping restore skin elasticity and reduce sagging.

• Smooths creases in high-expression zones like nasolabial folds and marionette lines while enhancing skin tone and radiance.

• Strengthens the skin barrier and supports natural hyaluronic acid synthesis for deep hydration and resilience.

• Gentle and effective: free of parabens, drying alcohols, and synthetic dyes. Dermatologically tested for mature and sensitive skin types.

Product Overview

A.G.E. Interrupter Advanced is a next-generation anti-wrinkle cream formulated to visibly reduce fine lines, improve skin firmness, and counteract the ageing effects of glycation—a natural process where excess sugars weaken collagen and elastin. This powerful anti-glycation treatment features:

• 12.6% Proxylane™ – A patented sugar-derived molecule that visibly improves skin density and supports moisture retention.

• 4.25% Wild Fruit Flavonoids – A potent antioxidant blend of blueberry and pomegranate extracts to combat oxidative stress and glycation.

• 0.1% Glycyrrhetinic Acid – A soothing, brightening agent that helps restore a healthy glow to dulled, aged skin.

• Niacinamide + HEPES – A powerful combination that supports cellular repair, exfoliation, and tone improvement.

Clinically proven to reduce multiple signs of ageing in 12 weeks:

• 14% reduction in fine lines

• 11.5% reduction in forehead wrinkles

• 11% reduction in nasolabial folds

• 7% reduction in crow’s feet, marionette lines, and glabellar wrinkles

The Science Behind Skin Glycation

Skin glycation is a key driver of accelerated ageing. It occurs when sugar molecules bind to collagen and elastin, forming advanced glycation end-products (A.G.E.s). These structures stiffen and degrade the skin’s support network, leading to:

• Fine lines and wrinkles

• Loss of skin firmness

• A dull, yellowish complexion

A.G.E. Interrupter Advanced directly targets this process, defending against further collagen breakdown while restoring youthful elasticity and radiance.

Glycation DOs & DON’Ts

• ✅ Do: Use daily SPF and antioxidant serums to protect against environmental accelerators of glycation.

• ✅ Do: Limit sugar and alcohol intake to reduce internal triggers.

• ❌ Don’t: Smoke or expose your skin to secondhand smoke, as it worsens oxidative damage and glycation.

Blemish + Age Defense Salicylic Acid Serum

An oil-free facial serum that improves blemish-prone skin while targeting visible signs of ageing.

Recommended For:

• Oily skin

• Acne-prone skin

• Combination skin

• Ageing skin

Product Benefits

• Regulates excess sebum production

• Helps control oiliness that contributes to clogged pores and breakouts.

• Improves skin clarity and texture

• Visibly reduces blotchiness, blemishes, and uneven skin tone for a smoother, more refined look.

• Decongests pores

• Effectively exfoliates and clears clogged pores, helping prevent future breakouts.

• Targets signs of ageing

• Diminishes the appearance of fine lines, wrinkles, and surface roughness.

• Ideal for adult breakouts

• A dual-action solution for those dealing with both acne and ageing concerns.

About the Product

Blemish + Age Defense is a powerful, oil-free serum designed for adult skin that’s both breakout-prone and affected by visible signs of ageing. This formula blends 2% dioic acid with a strategic combination of alpha-hydroxy acids (AHAs) and beta-hydroxy acids (BHAs), including salicylic, glycolic, and citric acids.

This multi-acid approach helps reduce the formation of blemishes, smooth the appearance of fine lines and wrinkles, and improve skin tone and radiance. By regulating excess oil and targeting roughness, this serum visibly improves skin texture and clarity.

Science + Clinical Results

• 39% reduction in sebum after 4 weeks

• 28% improvement in fine lines after 4 weeks

• As early as Day 2, noticeable improvements in:

  • Skin tone and clarity

  • Smoothness and brightness

  • Clogged pores and blemishes

  • Blotchiness

• Proven as effective and tolerable as 0.025% tretinoin, delivering statistically superior results in skin tone evenness, clarity, and blemish reduction.

• Post-inflammatory hyperpigmentation (PIH) was reduced by:

  • 19% after 4 weeks

  • 36% after 8 weeks

  • PIH spot count reduced by 29% after 8 weeks

Source: Baumann, L. (2013). JDD study comparing Blemish + Age Defense to clindamycin + benzoyl peroxide and tretinoin 0.025%.

The Science Behind Adult Blemishes

Adult breakouts are often triggered by hormonal shifts, stress, or environmental factors. Increased sebum production and impaired skin renewal contribute to clogged pores, blemishes, and post-inflammatory pigmentation.

Blemish + Age Defense addresses these root causes while also reducing fine lines and promoting a more youthful, even skin tone.

Adult Acne DOs + DON’Ts

• DO: Combine blemish and anti-ageing care.

  • AHAs like glycolic and citric acid target both blemishes and signs of ageing.

• DON’T: Use a one-size-fits-all approach.

  • Adult breakouts often require a multi-targeted solution that addresses hormonal and environmental factors.

Blemish-Fighting Partners

Pair Blemish + Age Defense with professional treatments like chemical peels to promote faster skin cell turnover. This serum complements in-clinic procedures by supporting long-term improvements in blemishes, texture, and radiance.

Overview

Epidermal Repair Soothing Cream is a targeted face cream formulated to support the skin’s natural moisture barrier and visibly reduce signs of sensitivity and redness. Ideal for compromised or post-procedural skin, this soothing cream helps calm irritation while restoring hydration and comfort to the skin.

Recommended For

• Dry skin

• Normal skin

• Sensitive or sensitised skin

• Dehydrated skin

• Visible blotchiness or redness

• Aging concerns

Key Benefits

• Restores Moisture Barrier

• Helps replenish and fortify the skin’s natural barrier, locking in moisture and improving hydration.

• Soothes Sensitivity

• Calms and comforts irritated or sensitised skin, especially following aesthetic procedures.

• Reduces Visible Redness

• Formulated to visibly diminish signs of blotchiness and redness.

• Post-Procedure Support

• Ideal for use after chemical peels, laser resurfacing, and IPL, supporting skin recovery and reducing downtime.

SkinCeuticals Glycolic 10 Renew Overnight Cream

Night-time glycolic acid cream for improved radiance, texture, and tone

Recommended For

• Dry skin

• Normal skin

• Oily skin

• Combination skin

• Ageing concerns

• Discolouration

Key Benefits

• Promotes skin cell turnover with 10% free acid value glycolic acid

• Improves visible skin texture, tone, and radiance

• Helps strengthen the skin’s moisture barrier

• Formulated with a triple-action soothing complex to enhance tolerability

• Complements professional chemical peels (individual suitability should be confirmed with a healthcare professional)

Product Overview

Glycolic 10 Renew Overnight is a corrective night cream that improves skin texture, tone, and radiance through the action of 10% free acid value glycolic acid. This optimal concentration supports exfoliation and promotes skin cell turnover while remaining gentle enough for nightly use. The formula is enhanced with 2% phytic acid and a triple-action soothing complex to help maintain moisture balance and skin comfort.

Science and Proof

In a clinical study, Glycolic 10 Renew Overnight demonstrated significant visible improvements in the following key indicators of healthy skin:

• 36% average improvement in radiance

• 37% average improvement in skin texture

• 19% average improvement in skin tone

Individual results may vary depending on skin type, condition, and use.

The Science Behind Glycolic 10 Renew Overnight

Cell turnover is a natural biological process in which the outer layer of skin sheds dead cells and replaces them with new ones. As this process slows with age, skin can appear dull, uneven, and more prone to visible signs of ageing. Glycolic acid, an alpha hydroxy acid (AHA), is widely used in skincare for its exfoliating and barrier-strengthening properties. Glycolic 10 Renew Overnight helps combat reduced cell turnover and supports brighter, smoother, and more resilient skin.

SkinCeuticals Hyaluronic Acid Intensifier Multi-Glycan

Volumising and Plumping Hyaluronic Acid Serum

Recommended For

• Dry

• Normal

• Combination

• Oily

• Sensitive

• Dehydrated

• Ageing

Key Benefits

• Immediately improves visible plumpness and skin radiance

• Visibly reduces fine lines and sagging

• Increases skin’s hyaluronic acid (HA) content by 30%

• Delivers 24-hour hydration boost

• Paraben-free, fragrance-free, and dye-free

• Suitable for all skin types

Product Overview

H.A. Intensifier Multi-Glycan is a next-generation, volumising serum formulated to enhance skin plumpness, hydration, and elasticity. Clinically proven to reduce the appearance of fine lines by up to 24%, this potent formula combines:

• 1.3% Pure Hyaluronic Acid for deep hydration

• 12% Proxylane™ to restore skin firmness and elasticity

• Post-biotic ferment extract to boost glycosaminoglycans, enhancing skin volume

Over time, skin appears visibly smoother, more defined, and radiant. Suitable for all skin types, including sensitive and ageing skin.

Visible Results

• 24% reduction in fine lines after 12 weeks of twice-daily use

• 10% immediate improvement in skin plumpness and radiance

• 30% increase in hyaluronic acid content

• 14% reduction in fine lines (cosmeto-clinical study)

• 7% visible improvement in skin sagging

Results observed in studies of over 140 participants aged 35–65.

The Science Behind H.A. Intensifier Multi-Glycan

Glycosaminoglycans (GAGs) and Skin Volume

GAGs, including hyaluronic acid, are naturally occurring compounds that maintain skin hydration and structure. As HA declines with age, skin can lose volume and elasticity. This serum stimulates glycan activity to restore firmness and visibly reduce wrinkles.

Next-Generation HA Complex

While most hyaluronic acid serums hydrate only the surface, this formula acts on multiple skin layers. The combination of three HA forms, Proxylane™, and post-biotic ferment extract targets both superficial and structural hydration, restoring facial volume and youthful plumpness.

SkinCeuticals Metacell Renewal B3

Daily anti-ageing treatment to promote skin renewal and reduce visible signs of photoageing.

Recommended For

• Dry

• Normal

• Oily

• Combination

• Sensitive

• Sensitised

• Dehydrated

• Discolouration

• Ageing

Product Benefit

Metacell Renewal B3 is a comprehensive daily face cream formulated to target early signs of photoageing and promote visible skin rejuvenation. This lightweight, non-greasy formulation helps to:

• Accelerate skin cell turnover to refine texture and improve radiance

• Visibly improve firmness and reduce the appearance of fine lines

• Strengthen the skin’s natural moisture barrier

• Address skin discolouration and uneven tone

• Deliver intense hydration without leaving skin feeling heavy or sticky

Clinical Results

A 12-week clinical study found significant improvements in signs of photoageing with twice-daily use of Metacell Renewal B3:

• 15% improvement in radiance and luminosity

• 20.9% reduction in fine lines

• 10.9% improvement in skin firmness

The Science Behind Metacell Renewal B3

Understanding Photoageing

Photoageing refers to premature ageing caused by prolonged UV exposure. Over time, this environmental stressor weakens skin cells, leading to wrinkles, discolouration, and loss of elasticity.

Key Preventive Measures

• DO: Apply broad-spectrum sunscreen daily — even indoors or on cloudy days — as UVA rays penetrate glass and cloud cover.

• DON’T: Prolong sun exposure during peak UV hours (10 a.m. – 4 p.m.).

Proven Pairing for Early Ageing

Combining Metacell Renewal B3 with treatments like Intense Pulsed Light (IPL) has been shown to improve skin tone, texture, and barrier function, while reducing transepidermal water loss.

SkinCeuticals Phyto Corrective Gel Soothing Serum

Hydrating and calming gel serum formulated with botanical extracts and hyaluronic acid to soothe, brighten, and visibly reduce redness.

Recommended For

• Dry

• Normal

• Oily

• Combination

• Sensitive

• Sensitised

• Dehydrated

• Discolouration

• Acne-prone

• Ageing skin

Key Benefits

• Formulated with anti-redness botanicals such as thyme and cucumber to comfort sensitised skin

• Eucalyptus extract helps minimise congestion by gently cleansing pores

• Mulberry extract visibly brightens and helps reduce the appearance of dark spots

• Olive leaf extract softens and nourishes skin

• Hyaluronic acid deeply hydrates and supports moisture retention

• Helps reduce visible redness and uneven skin tone

• Lightweight, non-greasy formulation suitable for all skin types

Product Overview

Phyto Corrective Gel Soothing Serum is a gentle hydrating serum designed to calm and rehydrate irritated or sensitive skin. Enriched with a botanical blend—including cucumber, thyme, olive leaf, and mulberry extract—this serum works to soothe inflammation, minimise redness, and visibly even skin tone. Hyaluronic acid adds deep hydration without heaviness, making this serum ideal for oily or redness-prone skin types.

Suitable for daily use, it helps strengthen the skin’s moisture barrier and restore balance to compromised or post-treatment skin. This calming serum also supports improved texture and clarity, making it a versatile addition to any skincare regimen targeting sensitivity, discolouration, or environmental stress.

Visible Results

In clinical and observational use, Phyto Corrective Gel Soothing Serum has shown visible improvement in:

• Redness reduction

• Overall tone and clarity

• Comfort and hydration in sensitised skin

SkinCeuticals Phyto Corrective Hydrating Mask

Intensive botanical hydrating mask designed to soothe, cool, and visibly comfort sensitive or post-procedure skin.

Recommended For

• Dry

• Oily

• Combination

• Normal

• Sensitive

• Sensitised

• Dehydrated

Key Benefits

• Delivers instant cooling and calming relief to hot, reactive, or irritated skin

• Restores hydration and radiance with hyaluronic acid and botanical extracts

• Proven to reduce visible redness and discomfort after cosmetic procedures

• Lightweight, oil-free gel texture suitable for post-exercise, sun exposure, and professional treatments

Product Description

SkinCeuticals Phyto Corrective Hydrating Mask is an intensive gel mask formulated with a high concentration of botanical extracts, dipeptides, and hyaluronic acid to provide immediate soothing and hydration for sensitised skin. Designed for versatility, this mask can be used after in-office procedures, environmental exposure, or daily skin stressors. It cools on contact and helps reduce the appearance of redness and discomfort, while promoting a smooth and radiant complexion.

Science & Proof

Clinically tested following non-ablative laser procedures.

• 20% reduction in visible redness

• 47% reduction in post-use discomfort

• 2.8°C average decrease in skin surface temperature

Individual results may vary. See protocol for details.

SkinCeuticals Retexturing Activator Exfoliating Serum

Bi-functional exfoliating and hydrating serum for smoother, more radiant skin

Recommended For

• Dry

• Normal

• Oily

• Combination

• Sensitive

• Sensitised

• Dehydrated

• Discolouration

• Acne

• Ageing

Product Benefits

Retexturing Activator Exfoliating Serum is a dual-action resurfacing treatment that exfoliates the skin while replenishing moisture. Formulated with a potent combination of hydroxyethyl urea and hyaluronic acid, it visibly improves skin texture, radiance, and hydration without irritation. Suitable for all skin types, this oil-free serum promotes healthy cell turnover, reduces the appearance of fine lines and discolouration, and strengthens the skin’s natural moisture barrier.

• Gently exfoliates while hydrating the skin

• Diminishes the appearance of surface lines and enhances skin smoothness

• Improves radiance and clarity

• Promotes optimal skin cell renewal

• Oil-free and non-irritating

• Clinically shown to outperform 20% glycolic acid treatment without the associated irritation

Science + Proof

Visible Results

In an 8-week, dermatologist-controlled study, Retexturing Activator exceeded the results of a daily 20% glycolic acid treatment, visibly improving surface lines and radiance with significantly less irritation.

The Science Behind Retexturing Activator

Accelerating Skin Cell Turnover

Skin cell turnover is the natural process of shedding dead skin cells and replacing them with new ones. This process slows with age or in acne-prone skin, leading to dullness, blocked pores, and visible signs of ageing.

Retexturing Activator contains hydroxyethyl urea, a powerful humectant that supports moisture retention and cell turnover, encouraging a healthier, smoother complexion.

Exfoliation Tips

• DO: Choose exfoliants based on your skin type.

  • Physical exfoliants are best for oily/combination skin.

  • Chemical exfoliants are gentler for sensitive skin and remove dead cells without abrasion.

• DON’T: Over-exfoliate.

  • Redness, irritation, or small bumps may indicate overuse. Adjust frequency based on skin response.

SkinCeuticals Retinol 0.3 Anti-Ageing Night Cream

A concentrated retinol night cream formulated with 0.3% pure retinol to promote skin cell turnover and visibly reduce signs of ageing, discolouration, pores, and blemishes.

Recommended For

• Normal skin

• Oily skin

• Combination skin

• Discolouration

• Blemishes

• Ageing concerns

Key Benefits

• Promotes Skin Cell Turnover

• Encourages exfoliation and renewal of the skin’s surface for a smoother, more refined complexion.

• Improves Visible Signs of Ageing

• Reduces the appearance of fine lines, wrinkles, discolouration, enlarged pores, and blemishes.

• Minimises Irritation

• Low concentration retinol formula includes bisabolol to help calm skin and reduce common side effects.

• Stable, Potent Delivery

• Specialised packaging protects retinol from degradation, maintaining stability and efficacy.

• Non-Comedogenic & Fragrance-Free

• Suitable for all skin types, including sensitive or acne-prone skin.

• Ideal for Retinol Beginners

• A gentle yet effective concentration for those new to retinol or transitioning to higher strengths.

Product Overview

SkinCeuticals Retinol 0.3 Anti-Ageing Night Cream is ideal for first-time retinol users seeking to improve skin clarity, texture, and tone. This dermatologist-recommended formula uses 0.3% pure retinol with a targeted delivery system to reduce visible signs of ageing while supporting skin renewal. The formula is enhanced with bisabolol to soothe skin and help minimise irritation, while the protective packaging ensures maximum retinol potency. It may also be used as a preparatory step before advancing to SkinCeuticals Retinol 0.5.

Science + Proof

Visible Results

In clinical observation, regular use of Retinol 0.3 has been shown to:

• Reduce the appearance of fine lines and wrinkles

• Improve skin tone and texture

• Address mild to moderate acne concerns

• Visibly minimise discolouration and enlarged pores

Accelerating Skin Cell Turnover

Retinol works by stimulating the natural shedding of dead skin cells and accelerating the renewal of new ones. This process reduces visible signs of ageing, smooths skin texture, and refines pores. Retinol 0.3 utilises an advanced stabilisation system to ensure optimal delivery and long-term effectiveness.

Getting Started with Retinol

Retinol is a potent derivative of vitamin A and requires gradual introduction into your skincare routine. SkinCeuticals recommends the following approach to minimise the risk of irritation:

The Sandwich Method

A layering technique designed to buffer retinol and retain moisture.

• Cleanse and apply a hydrating serum or lightweight moisturiser.

• Apply a small amount of Retinol 0.3 to dry skin.

• Follow with a barrier-repair moisturiser such as Triple Lipid Restore 2:4:2.

Product Details:

Retinol 0.5 contains 0.5% pure retinol and is enhanced with the latest stabilization and delivery technologies to ensure the full dosage is slowly and evenly released. Designed to help diminish the appearance of fine lines, wrinkles, and skin discoloration. This night cream can minimize the appearance of pore size, while reducing the appearance of blemishes associated with problematic skin. Retinol 0.5 is recommended for first-time retinol cream users and is ideal for continued use or for conditioning skin as a prerequisite to SkinCeuticals Retinol 1.0.

Features & Benefits:

• Helps to reduce the appearance of fine lines, skin discolouration, blemishes and blotchiness

• Ageing and acne-prone skin can benefit from the use of this stable formula, which has been created to minimise irritation sometimes associated with the use of retinol creams.

• This Retinol Night Cream is non-comedogenic and won’t block pores. The wide-ranging retinol benefits are suitable for all skin-types.

SkinCeuticals Retinol 1.0 Anti-Ageing Night Cream

A high-concentration pure retinol 1% cream formulated to refine the visible signs of ageing and improve skin clarity. Recommended for experienced retinol users only.

Recommended For

• Normal

• Oily

• Combination

• Discolouration

• Acne-prone

• Ageing

Product Benefits

• Promotes skin cell turnover

• Visibly improves the appearance of fine lines, wrinkles, discolouration, and blemishes

• Formulated with a soothing complex to help minimise irritation commonly associated with high-strength retinol

• Advanced packaging preserves retinol stability and potency

• Non-comedogenic and free from parabens, fragrance, alcohol*, and dyes

• (*Contains no ethylic alcohol)

• Ideal for skin preconditioned with Retinol 0.5

Product Description

Retinol 1.0 Anti-Ageing Night Cream is designed for experienced retinol users seeking more advanced results. With 1% pure retinol in a stabilised format, this high-strength formula supports visible improvements in skin tone, texture, fine lines, and post-acne pigmentation. The cream also targets pore visibility and congestion while encouraging cell renewal for a healthier, more refined complexion.

To avoid irritation, it is essential to pair Retinol 1.0 with a lipid-rich moisturiser such as Triple Lipid Restore 2:4:2. It should only be applied at night and requires a consistent broad-spectrum sunscreen during the day due to increased photosensitivity.

Science + Proof

Visible Results

Topical 1% retinol application is clinically shown to reduce fine lines, wrinkles, uneven skin tone, and pigmentation associated with acne-prone skin. It also helps to minimise the occurrence of blemishes and refine skin texture.

The Science Behind Retinol 1.0

Combat Reduced Skin Cell Turnover

As we age, our skin’s natural renewal process slows, contributing to visible signs of ageing and congestion. Retinol helps accelerate this process, improving the skin’s tone and clarity. The 1.0 formula uses an optimised delivery system that aligns with the skin’s lipid barrier for enhanced absorption and efficacy.

Advanced Strength Retinol

Once skin has adapted to lower concentrations (0.3% and 0.5%), Retinol 1.0 offers a potent step up, helping to address deeper wrinkles, stubborn discolouration, and texture irregularities more effectively.

Retinol Application Tip: The Sandwich Method

To support the skin barrier while maximising results:

• Prep: Cleanse and apply a hydrating serum or moisturiser. Allow to fully absorb.

• Treat: Apply a small amount of Retinol 1.0 to targeted areas.

• Seal: Finish with a rich moisturiser like Triple Lipid Restore 2:4:2 to lock in hydration and reduce irritation.

SkinCeuticals Triple Lipid Restore 2:4:2 Anti-Ageing Moisturiser

Ceramide Face Cream with Lipids to Nourish & Hydrate Dry Skin

Recommended For

• Dry

• Normal

• Oily

• Combination

• Sensitive

• Dehydrated

• Ageing

Triple Lipid Restore 2:4:2 Benefits

• Restores essential skin lipids

• Formulated with a patented ratio of 2% ceramides, 4% cholesterol, and 2% fatty acids to support the skin barrier.

• Improves fullness, texture and pore appearance

• Helps restore a plump, refined look to the skin with improved tone and surface smoothness.

• Enhances skin evenness and radiance

• Targets visible signs of ageing such as dullness, blotchiness, and uneven tone.

• Reduces retinol-related dryness

• Clinically shown to shorten the retinol adjustment period by up to one week.

• Fast-absorbing and lightweight

• Unique lipid stabilisation system provides high-performance hydration in a non-greasy finish.

Product Description

SkinCeuticals Triple Lipid Restore 2:4:2 is a lipid-rich anti-ageing moisturiser formulated with a precisely balanced ratio of 2% ceramides, 4% natural cholesterol, and 2% fatty acids. This ceramide face cream helps restore skin’s natural barrier, nourish dry or ageing skin, and support visible improvement in elasticity, tone, and radiance. Its science-backed formulation addresses the lipid depletion that naturally occurs with age, improving the appearance of wrinkles, fullness, and smoothness.

SCIENCE + PROOF

Visible Results

Clinical testing of Triple Lipid Restore 2:4:2 found:

• 66% improvement in skin smoothness

• 35% improvement in skin laxity

• 26% improvement in radiance

• 20% improvement in skin evenness

• 44% improvement in pore appearance

A secondary lipidomic analysis also revealed:

• 57% increase in ceramides

• 50% increase in cholesterol

• 12% increase in fatty acids (as triglycerides)

The Science Behind Triple Lipid Restore 2:4:2

What Is Lipid Depletion?

As we age, the skin’s production of ceramides, cholesterol, and fatty acids declines. This lipid loss weakens the skin’s barrier, leading to rough texture, visible signs of accelerated ageing, and reduced self-repair. Restoring these lipids helps re-strengthen the barrier and restore radiance.

2:4:2 Ingredient Ratio

SkinCeuticals’ 2:4:2 formulation replicates the optimal balance of lipids found in healthy, youthful skin. This cholesterol-dominant ratio supports repair while improving softness, elasticity, and skin comfort.

Triple Lipid Restore + Tretinoin

Tretinoin, a prescription-strength retinoid, is known to cause dryness and irritation during the adjustment period. Triple Lipid Restore 2:4:2 is clinically shown to reduce discomfort and dryness during this phase, supporting treatment adherence and outcomes.

How to Use With Retinol or Tretinoin (The Sandwich Method)

• Cleanse + Pre-Moisturise

• Begin with a gentle cleanser, then apply a hydrating serum or thin layer of moisturiser.

• Apply Retinol or Tretinoin

• Use a pea-sized amount of your retinoid treatment.

• Seal With Triple Lipid Restore 2:4:2

• Finish with a layer of Triple Lipid Restore to trap moisture, reduce irritation, and enhance treatment effectiveness.

SkinCeuticals Ultra Facial Defense Sunscreen SPF50

SPF50+ broad-spectrum facial sunscreen for very high-level protection against UVA/UVB rays with an ultra-moisturising formula.

RECOMMENDED FOR

• Dry

• Normal

• Oily

• Combination

• Sensitive

• Sensitised

• Dehydrated

• Discolouration

• Ageing

Ultra Facial Defense Sunscreen Benefits

Packaged in a portable design, our easy-to-apply broad-spectrum sunscreen is formulated with a lightweight and comfortable texture.

Absorbent without leaving a residue, Ultra Facial Defence SPF 50+ provides very high sun protection.

This SPF 50+ sunscreen is non-comedogenic and won’t clog pores, making it suitable for every skin type.

Ultra Facial Defense Sunscreen SPF 50

Ultra Facial Defence SPF 50+ sunscreen protects skin from UVA/UVB rays known to cause damage and premature ageing. This SPF 50+ for face provides very high sunscreen protection. Our UV filters work synergistically to prevent photodamage — a skin alteration caused as a result of prolonged exposure to the sun. Ideal for all skin types, the uniquely ultra-light moisturising texture provides 24-hour hydration.

SkinCeuticals Hydrating B5 Hyaluronic Acid Facial Mask

Intensely hydrating weekly gel mask to replenish moisture levels. 

RECOMMENDED FOR

• Dry

• Normal

• Oily

• Combination

• Dehydrated

• Acne-Prone

• Ageing 

Hydrating B5 Mask Benefits

• Optimises moisture infusion in targeted areas

• Improves skin’s tissue repair function

• Plumps and replenishes skin

• Ideal for all skin types 

Hydrating B5 Hyaluronic Acid Facial Mask

Inspired by the award-winning Hydrating B5 Serum, this face mask contains 1% hyaluronic acid and a rich concentration of vitamin B5 to replenish depleted moisture levels in dehydrated and tired skin. 

Vitamin B5 (also known as pantothenic acid) helps moisturise, soothe and stimulate the repair of skin. The full effectiveness of vitamin B5 is achieved when the ingredient penetrates the skin. 

SkinCeuticals developed this hyaluronic acid and vitamin B face mask to enable these potent ingredients to infuse deeply into the skin tissue. 

The hydrating mask can be applied to the face, neck, chest and body to restore moisture levels, visibly repair tissue and leave skin feeling soft and supple.

Gentle Cleanser is a creamy, mild cleanser formulated with an emollient-rich surfactant and a 3% concentration combining allantoin, glycerin, and orange oil to soften and restore skin’s surface.  This non-foaming, gentle skin cleanser efficiently removes impurities and long-wear face and eye makeup without any traces of residue.  Skin is left feeling soft, moisturised, and primed.

• Softens skin while cleansing and lifting surface debris

• Removes long-wear eye and face makeupNon-comedogenic formula ideal for daily use

• Paraben-, sulfate-, soap-, synthetic-fragrance-, dye- and alcohol-free

• Suitable for dry, normal, sensitive, reactive, or post-procedure skin

Glycolic 10 Renew Overnight improves the appearance of skin texture and tone for a brighter complexion and radiant skin. This scientifically developed glycolic acid cream has a free acid value of 10%, meaning it works at a true 10% concentration – optimal for promoting exfoliation and skin cell turnover. Synergistically blended with 2% phytic acid and a triple action comforting complex to help support the skin barrier, this glycolic acid night cream is suitable for nightly use. 

Features & Benefits:

• This night cream promotes cellular turnover with 10% free acid value glycolic acid with a dye free formula tested for use every night.

• The Glycolic 10 Renew Overnight cream makes for an ideal complement to chemical peels, however you should always consult with a healthcare professional for individual recommendations.

Blemish + Age Cleanser is a targeted exfoliating gel cleanser featuring a conditioning surfactant and a 12% concentration combining lipo-hydroxy acid (LHA), glycolic acid , salicylic acid, glycerin, and sorbitol, to remove excess oils and makeup, while decongesting pores and brightening skin. Formulated for ageing skin prone to breakouts, this deep cleansing gel gently refines the visible appearance of congested pores and helps reduce blemishes without drying the skin. 

• Features a blend of acids to address breakouts and visible signs of ageing

• Delivers even exfoliation to unclog congested pores

• Removes excess oil and makeup

• Soap-, synthetic fragrance-, dye- and alcohol*-free (*No ethylic alcohol)S

• uitable for oily, combination, and ageing skin types